The artist has handed over the complete sum of his £25k honor prize money to the MVT, which works to save the United Kingdom's small music venues.
He was given the award on October 16 as his third album People Watching was declared the best record of the previous year.
Fender has chosen to give the cash to the Music Venues Trust, in recognition of the crucial part grassroots venues played in his beginning days.
"I would not have achieved my current career if it weren't for all the performances I did around the North East, and beyond, when I was beginning," said the artist. "These spaces are renowned, but they are in difficulty."
Beginning in 2023, at least 150 of these locations have ceased operations – roughly 16 percent of the entire UK sector.
Recently, major artists like Pulp, Coldplay, Katy Perry and Ed Sheeran have all supported the trust in its initiatives to help venues survive, by applying a small levy to their admission fees, which goes to help independent venues.
Sam Fender also participated, collecting more than £100,000 on his recent tour to help numerous grassroots venues across Britain.
These funds supported locations that were facing potential shutdown due to difficulties stemming from flooding, blazes and bereavements, as well as regulatory hurdles, legal disputes and neighbor objections.
Some locations obtained financial assistance in upgrading infrastructure and sound and lighting systems that directly benefitted artists and audiences.
"The idea that funds from shows in major spaces backs the local stages, where it all starts for musicians like me, is just common sense," the star has stated.
He is among several artists to contribute his award prize money to charitable organizations.
In Pulp received the award in the year 1996 for their record Different Class, vocalist Jarvis Cocker stated that the act would give their prize money to the non-profit the charity.
That year, artist the artist shared her bounty between a few organizations, including the NSPCC and a Sickle Cell organization.
"Additionally, I contributed a thousand pounds to Highgate Newtown, to their classes, because I trained in gymnastics when I was a child and they needed updated gear," she shared with the media.
Two years ago, Ezra Collective contributed their prize money to the local youth club that nurtured their act, in addition to other independent music bodies.
And the 1994 recipients M People contributed their prize to a multiple sclerosis charity after a close contact was diagnosed the condition.
"The victory was quite enough," remarked vocalist Heather Small. "The cash was the cherry on top but we could do without the cherry, because we had the cake. So our success touched the lives of others."
Last week, the Music Venues Trust shared it had saved several local spots in south-east England, by bringing them into community ownership.
The first in the city and the other in that location were purchased under the community ownership scheme, which is backed by a national body and music fans who acquire "ownership units" in the properties.